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Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis

Background: Leishmaniases are neglected diseases caused by infection with Leishmania parasites and there are no human vaccines in use routinely. The purpose of this study was to examine the immunogenicity of ChimeraT, a novel synthetic recombinant vaccine against visceral leishmaniasis (VL), incorpo...

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Detalles Bibliográficos
Autores principales: Lage, Daniela P., Ribeiro, Patrícia A.F., Dias, Daniel S., Mendonça, Débora V.C., Ramos, Fernanda F., Carvalho, Lívia M., Steiner, Bethina T., Tavares, Grasiele S.V., Martins, Vívian T., Machado, Amanda S., Oliveira-da-Silva, João A., Santos, Thaís T.O., Freitas, Camila S., Oliveira, Jamil S., Roatt, Bruno M., Machado-de-Ávila, Ricardo A., Humbert, Maria V., Christodoulides, Myron, Coelho, Eduardo A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349940/
https://www.ncbi.nlm.nih.gov/pubmed/32526867
http://dx.doi.org/10.3390/vaccines8020289