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Uncovering Distinct Primary Vaccination-Dependent Profiles in Human Bordetella pertussis Specific CD4+ T-Cell Responses Using a Novel Whole Blood Assay

To advance research and development of improved pertussis vaccines, new immunoassays are needed to qualify the outcome of Bordetella pertussis (Bp) specific CD4+ T-cell differentiation. Here, we applied a recently developed whole blood assay to evaluate Bp specific CD4+ T-cell responses. The assay i...

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Detalles Bibliográficos
Autores principales: Lambert, Eleonora E., Corbière, Véronique, van Gaans-van den Brink, Jacqueline A. M., Duijst, Maxime, Venkatasubramanian, Prashanna Balaji, Simonetti, Elles, Huynen, Martijn, Diavatopoulos, Dimitri D., Versteegen, Pauline, Berbers, Guy A. M., Mascart, Françoise, van Els, Cécile A. C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349943/
https://www.ncbi.nlm.nih.gov/pubmed/32429152
http://dx.doi.org/10.3390/vaccines8020225