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Uncovering Distinct Primary Vaccination-Dependent Profiles in Human Bordetella pertussis Specific CD4+ T-Cell Responses Using a Novel Whole Blood Assay
To advance research and development of improved pertussis vaccines, new immunoassays are needed to qualify the outcome of Bordetella pertussis (Bp) specific CD4+ T-cell differentiation. Here, we applied a recently developed whole blood assay to evaluate Bp specific CD4+ T-cell responses. The assay i...
Autores principales: | Lambert, Eleonora E., Corbière, Véronique, van Gaans-van den Brink, Jacqueline A. M., Duijst, Maxime, Venkatasubramanian, Prashanna Balaji, Simonetti, Elles, Huynen, Martijn, Diavatopoulos, Dimitri D., Versteegen, Pauline, Berbers, Guy A. M., Mascart, Françoise, van Els, Cécile A. C. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349943/ https://www.ncbi.nlm.nih.gov/pubmed/32429152 http://dx.doi.org/10.3390/vaccines8020225 |
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