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Recombinant Costimulatory Fusion Proteins as Functional Immunomodulators Enhance Antitumor Activity in Murine B16F10 Melanoma

Blocking inhibitory signaling and engaging stimulatory signaling have emerged as important therapeutic modalities for cancer immunotherapy. This study aimed to investigate immunomodulatory features of three recombinant costimulatory ligand proteins in a mouse model, which are extracellular domains o...

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Detalles Bibliográficos
Autores principales: Cai, Huaman, Wang, Wenfang, Lin, Zhibing, Zhang, Yan, Wu, Bing, Wan, Yuhua, Li, Rongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349950/
https://www.ncbi.nlm.nih.gov/pubmed/32423130
http://dx.doi.org/10.3390/vaccines8020223