Orf Virus-Based Vaccine Vector D1701-V Induces Strong CD8+ T Cell Response against the Transgene but Not against ORFV-Derived Epitopes

The potency of viral vector-based vaccines depends on their ability to induce strong transgene-specific immune response without triggering anti-vector immunity. Previously, Orf virus (ORFV, Parapoxvirus) strain D1701-V was reported as a novel vector mediating protection against viral infections. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Reguzova, Alena, Ghosh, Michael, Müller, Melanie, Rziha, Hanns-Joachim, Amann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349966/
https://www.ncbi.nlm.nih.gov/pubmed/32531997
http://dx.doi.org/10.3390/vaccines8020295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349966/
https://www.ncbi.nlm.nih.gov/pubmed/32531997
http://dx.doi.org/10.3390/vaccines8020295

Ejemplares similares