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Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T cells that Trigger Protection against Experimental Visceral Leishmaniasis

Many vaccine candidates against visceral leishmaniasis (VL) have been proposed; however, to date, none of them have been efficacious for the human or canine disease. On this basis, the design of leishmaniasis vaccines has been constantly changing, and the use of approaches to select specific epitope...

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Detalles Bibliográficos
Autores principales: De Brito, Rory Cristiane Fortes, Ruiz, Jeronimo Conceição, Cardoso, Jamille Mirelle de Oliveira, Ostolin, Thais Lopes Valentim Di Paschoale, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Resende, Daniela de Melo, Reis, Alexandre Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349981/
https://www.ncbi.nlm.nih.gov/pubmed/32471081
http://dx.doi.org/10.3390/vaccines8020252