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Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines

Hypochlorous acid (HOCl)-treated whole tumor cell lysates (Ox-L) have been shown to be more immunogenic when used as an antigen source for therapeutic dendritic cell (DC)-based vaccines, improving downstream immune responses both in vitro and in vivo. However, the mechanisms behind the improved immu...

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Detalles Bibliográficos
Autores principales: Graciotti, Michele, Marino, Fabio, Pak, HuiSong, Baumgaertner, Petra, Thierry, Anne-Christine, Chiffelle, Johanna, Perez, Marta A. S., Zoete, Vincent, Harari, Alexandre, Bassani-Sternberg, Michal, Kandalaft, Lana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349990/
https://www.ncbi.nlm.nih.gov/pubmed/32498431
http://dx.doi.org/10.3390/vaccines8020271