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Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines
Hypochlorous acid (HOCl)-treated whole tumor cell lysates (Ox-L) have been shown to be more immunogenic when used as an antigen source for therapeutic dendritic cell (DC)-based vaccines, improving downstream immune responses both in vitro and in vivo. However, the mechanisms behind the improved immu...
Autores principales: | Graciotti, Michele, Marino, Fabio, Pak, HuiSong, Baumgaertner, Petra, Thierry, Anne-Christine, Chiffelle, Johanna, Perez, Marta A. S., Zoete, Vincent, Harari, Alexandre, Bassani-Sternberg, Michal, Kandalaft, Lana E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349990/ https://www.ncbi.nlm.nih.gov/pubmed/32498431 http://dx.doi.org/10.3390/vaccines8020271 |
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