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Safety Surveillance of Pneumococcal Vaccine Using Three Algorithms: Disproportionality Methods, Empirical Bayes Geometric Mean, and Tree-Based Scan Statistic

Introduction: Diverse algorithms for signal detection exist. However, inconsistent results are often encountered among the algorithms due to different levels of specificity used in defining the adverse events (AEs) and signal threshold. We aimed to explore potential safety signals for two pneumococc...

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Detalles Bibliográficos
Autores principales: Lee, Hyesung, Kim, Ju Hwan, Choe, Young June, Shin, Ju-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349998/
https://www.ncbi.nlm.nih.gov/pubmed/32456068
http://dx.doi.org/10.3390/vaccines8020242