Cargando…

GM1 as Adjuvant of Innovative Therapies for Cystic Fibrosis Disease

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein is expressed at the apical plasma membrane (PM) of different epithelial cells. The most common mutation responsible for the onset of cystic fibrosis (CF), F508del, inhibits the biosynthesis and transport of the protein at PM, and als...

Descripción completa

Detalles Bibliográficos
Autores principales: Mancini, Giulia, Loberto, Nicoletta, Olioso, Debora, Dechecchi, Maria Cristina, Cabrini, Giulio, Mauri, Laura, Bassi, Rosaria, Schiumarini, Domitilla, Chiricozzi, Elena, Lippi, Giuseppe, Pesce, Emanuela, Sonnino, Sandro, Pedemonte, Nicoletta, Tamanini, Anna, Aureli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350007/
https://www.ncbi.nlm.nih.gov/pubmed/32599772
http://dx.doi.org/10.3390/ijms21124486