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Lipidation of Pneumococcal Antigens Leads to Improved Immunogenicity and Protection

Streptococcus pneumoniae infections lead to high morbidity and mortality rates worldwide. Pneumococcal polysaccharide conjugate vaccines significantly reduce the burden of disease but have a limited range of protection, which encourages the development of a broadly protective protein-based alternati...

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Detalles Bibliográficos
Autores principales: Voß, Franziska, van Beek, Lucille F., Schwudke, Dominik, Ederveen, Thomas H. A., van Opzeeland, Fred J., Thalheim, Daniela, Werner, Sidney, de Jonge, Marien I., Hammerschmidt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350230/
https://www.ncbi.nlm.nih.gov/pubmed/32560374
http://dx.doi.org/10.3390/vaccines8020310