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Innovative Three-Dimensional Microscopic Analysis of Uremic Growth Plate Discloses Alterations in the Process of Chondrocyte Hypertrophy: Effects of Growth Hormone Treatment

Chronic kidney disease (CKD) alters the morphology and function of the growth plate (GP) of long bones by disturbing chondrocyte maturation. GP chondrocytes were analyzed in growth-retarded young rats with CKD induced by adenine intake (AD), control rats fed ad libitum (C) or pair-fed with the AD gr...

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Detalles Bibliográficos
Autores principales: Fernández-Iglesias, Ángela, Fuente, Rocío, Gil-Peña, Helena, Alonso-Durán, Laura, García-Bengoa, María, Santos, Fernando, López, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350242/
https://www.ncbi.nlm.nih.gov/pubmed/32630463
http://dx.doi.org/10.3390/ijms21124519