The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

Oncogenic activation of the phosphatidylinositol-3-kinase (PI3K), protein kinase B (PKB/AKT), and mammalian target of rapamycin (mTOR) pathway is a frequent event in prostate cancer that facilitates tumor formation, disease progression and therapeutic resistance. Recent discoveries indicate that the...

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Detalles Bibliográficos
Autores principales: Shorning, Boris Y., Dass, Manisha S., Smalley, Matthew J., Pearson, Helen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350257/
https://www.ncbi.nlm.nih.gov/pubmed/32630372
http://dx.doi.org/10.3390/ijms21124507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350257/
https://www.ncbi.nlm.nih.gov/pubmed/32630372
http://dx.doi.org/10.3390/ijms21124507

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