Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment

The tumor microenvironment (TME) comprises different types of immune cells, which limit the therapeutic efficacy of most drugs. Although oncolytic virotherapy (OVT) boosts antitumor immunity via enhanced infiltration of tumor-infiltrated lymphocytes (TILs), immune checkpoints on the surface of tumor...

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Detalles Bibliográficos
Autores principales: Yoo, So Young, Badrinath, Narayanasamy, Jeong, Su-Nam, Woo, Hyun Young, Heo, Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350271/
https://www.ncbi.nlm.nih.gov/pubmed/32575351
http://dx.doi.org/10.3390/vaccines8020321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350271/
https://www.ncbi.nlm.nih.gov/pubmed/32575351
http://dx.doi.org/10.3390/vaccines8020321

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