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Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment
The tumor microenvironment (TME) comprises different types of immune cells, which limit the therapeutic efficacy of most drugs. Although oncolytic virotherapy (OVT) boosts antitumor immunity via enhanced infiltration of tumor-infiltrated lymphocytes (TILs), immune checkpoints on the surface of tumor...
Autores principales: | Yoo, So Young, Badrinath, Narayanasamy, Jeong, Su-Nam, Woo, Hyun Young, Heo, Jeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350271/ https://www.ncbi.nlm.nih.gov/pubmed/32575351 http://dx.doi.org/10.3390/vaccines8020321 |
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