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Seneca Valley Virus 3C(pro) Cleaves PABPC1 to Promote Viral Replication

Seneca Valley Virus (SVV) is an oncolytic virus of the Picornaviridae family, which has emerged in recent years. The impact of SVV on host cell translation remains unknown. Here, we showed, for the first time, that SVV infection cleaved poly(A) binding protein cytoplasmic 1 (PABPC1). In SVV-infected...

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Detalles Bibliográficos
Autores principales: Xue, Qiao, Liu, Huisheng, Zhu, Zixiang, Xue, Zhaoning, Liu, Xiangtao, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350346/
https://www.ncbi.nlm.nih.gov/pubmed/32512928
http://dx.doi.org/10.3390/pathogens9060443