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Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands

Members of the tumour necrosis factor (TNF) superfamily OX40L and CD70 and their receptors are costimulating signalling axes critical for adequate T cell activation in humans and mice but characterisation of these molecules in other species including ruminants is lacking. Here we cloned and expresse...

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Detalles Bibliográficos
Autores principales: Rojas, José Manuel, Alejo, Alí, Avia, Jose Miguel, Rodríguez-Martín, Daniel, Sánchez, Carolina, Alcamí, Antonio, Sevilla, Noemí, Martín, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350415/
https://www.ncbi.nlm.nih.gov/pubmed/32580486
http://dx.doi.org/10.3390/vaccines8020333