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Quantitative characterization of tumor cell-free DNA shortening

BACKGROUND: Previous studies found that cell-free DNA (cfDNA) generated from tumors was shorter than that from healthy cells, and selecting short cfDNA could enrich for tumor cfDNA and improve its usage in early cancer diagnosis and treatment monitoring; however, the underlying mechanism of shortene...

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Detalles Bibliográficos
Autores principales: Guo, Juntang, Ma, Kefeng, Bao, Hua, Ma, Xiangyuan, Xu, Yang, Wu, Xue, Shao, Yang W., Jiang, Mei, Huang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350596/
https://www.ncbi.nlm.nih.gov/pubmed/32650715
http://dx.doi.org/10.1186/s12864-020-06848-9