Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Opioid abuse alters the functions of immune cells in both in vitro and in vivo systems, including macrophages. Here, we investigated the effects of methadone, a widely used opioid receptor agonist for treatment of opiate addiction, on the expression of intracellular viral restriction factors and HIV...

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Detalles Bibliográficos
Autores principales: Wang, Mei-Rong, Wu, Di-Di, Luo, Fan, Zhong, Chao-Jie, Wang, Xin, Zhu, Ni, Wu, Ying-Jun, Hu, Hai-Tao, Feng, Yong, Wang, Xu, Xiong, Hai-Rong, Hou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350609/
https://www.ncbi.nlm.nih.gov/pubmed/32719674
http://dx.doi.org/10.3389/fimmu.2020.01253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350609/
https://www.ncbi.nlm.nih.gov/pubmed/32719674
http://dx.doi.org/10.3389/fimmu.2020.01253

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