MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function

BACKGROUND: Foxp3(+)CD4(+) regulatory T cells (Treg) constitutes a key event in autoimmune diseases. STAT5b is the critical link between the IL-2/15 and FOXP3, the master regulator of Treg cells. METHODS: The CD3(+)T cell and Foxp3(+)CD4(+) regulatory T cells were overexpressioned or knockdown MKL-1...

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Detalles Bibliográficos
Autores principales: Xiang, Yuan, Wang, Jun, Li, Jia Peng, Guo, Wei, Huang, Feng, Zhang, Hui Min, Li, Han Han, Dai, Zhou Tong, Zhang, Zi Jian, Li, Hui, Bao, Le Yuan, Gu, Chao Jiang, Chen, Kun, Zhang, Tong Cun, Liao, Xing Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350762/
https://www.ncbi.nlm.nih.gov/pubmed/32646440
http://dx.doi.org/10.1186/s12964-020-00574-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350762/
https://www.ncbi.nlm.nih.gov/pubmed/32646440
http://dx.doi.org/10.1186/s12964-020-00574-1

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