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Deep sequencing reveals new roles for MuB in transposition immunity and target-capture, and redefines the insular Ter region of E. coli

BACKGROUND: The target capture protein MuB is responsible for the high efficiency of phage Mu transposition within the E. coli genome. However, some targets are off-limits, such as regions immediately outside the Mu ends (cis-immunity) as well as the entire ~ 37 kb genome of Mu (Mu genome immunity)....

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Detalles Bibliográficos
Autores principales: Walker, David M., Harshey, Rasika M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350765/
https://www.ncbi.nlm.nih.gov/pubmed/32670425
http://dx.doi.org/10.1186/s13100-020-00217-9