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Antinociceptive Effect of Liposomal Bupivacaine Formulations After Intrathecal Administration in Rats

BACKGROUND/AIM: Based on our previous in vitro study with multilamellar liposomal bupivacaine (MLB) versus bupivacaine alone in artificial cerebrospinal fluid, we aimed to investigate in vivo antinociceptive effect of intrathecal MLB by determining tail flick latency (TFL) time after thermal stimula...

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Detalles Bibliográficos
Autores principales: YİĞİT, İlker, GÜNAYDIN, Berrin, O. EMMEZ, Hakan, ULUDAĞ, Orhan, BAL, Nur Banu, DEĞİM, Tuncer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350835/
https://www.ncbi.nlm.nih.gov/pubmed/30761835
http://dx.doi.org/10.3906/sag-1806-200