Acetaminophen Use Concomitant with Long-Lasting Flucloxacillin Therapy: A Dangerous Combination

Acetaminophen and flucloxacillin both interfere with the γ-glutamyl cycle. Long-lasting concomitant use of flucloxacillin and acetaminophen can lead to 5-oxoproline accumulation and severe high anion gap metabolic acidosis. Females and patients with sepsis, impaired kidney and/or liver function, mal...

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Detalles Bibliográficos
Autores principales: van den Bersselaar, Luuk René, van den Brule, Judith Maria Dimphena, van der Hoeven, Johannes Gerardus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350975/
https://www.ncbi.nlm.nih.gov/pubmed/32665925
http://dx.doi.org/10.12890/2020_001569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350975/
https://www.ncbi.nlm.nih.gov/pubmed/32665925
http://dx.doi.org/10.12890/2020_001569

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