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Acetaminophen Use Concomitant with Long-Lasting Flucloxacillin Therapy: A Dangerous Combination
Acetaminophen and flucloxacillin both interfere with the γ-glutamyl cycle. Long-lasting concomitant use of flucloxacillin and acetaminophen can lead to 5-oxoproline accumulation and severe high anion gap metabolic acidosis. Females and patients with sepsis, impaired kidney and/or liver function, mal...
Autores principales: | van den Bersselaar, Luuk René, van den Brule, Judith Maria Dimphena, van der Hoeven, Johannes Gerardus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350975/ https://www.ncbi.nlm.nih.gov/pubmed/32665925 http://dx.doi.org/10.12890/2020_001569 |
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