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Chromosome-level de novo assembly of the pig-tailed macaque genome using linked-read sequencing and HiC proximity scaffolding

BACKGROUND: Macaque species share >93% genome homology with humans and develop many disease phenotypes similar to those of humans, making them valuable animal models for the study of human diseases (e.g., HIV and neurodegenerative diseases). However, the quality of genome assembly and annotation...

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Detalles Bibliográficos
Autores principales: Roodgar, Morteza, Babveyh, Afshin, Nguyen, Lan H, Zhou, Wenyu, Sinha, Rahul, Lee, Hayan, Hanks, John B, Avula, Mohan, Jiang, Lihua, Jian, Ruiqi, Lee, Hoyong, Song, Giltae, Chaib, Hassan, Weissman, Irv L, Batzoglou, Serafim, Holmes, Susan, Smith, David G, Mankowski, Joseph L, Prost, Stefan, Snyder, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350979/
https://www.ncbi.nlm.nih.gov/pubmed/32649757
http://dx.doi.org/10.1093/gigascience/giaa069