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Tuning GABAergic Inhibition: Gephyrin Molecular Organization and Functions
To be highly reliable, synaptic transmission needs postsynaptic receptors (Rs) in precise apposition to the presynaptic release sites. At inhibitory synapses, the postsynaptic protein gephyrin self-assembles to form a scaffold that anchors glycine and GABA(A)Rs to the cytoskeleton, thus ensuring the...
Autores principales: | Pizzarelli, Rocco, Griguoli, Marilena, Zacchi, Paola, Petrini, Enrica Maria, Barberis, Andrea, Cattaneo, Antonino, Cherubini, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351109/ https://www.ncbi.nlm.nih.gov/pubmed/31356900 http://dx.doi.org/10.1016/j.neuroscience.2019.07.036 |
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