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GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation

Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients wit...

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Detalles Bibliográficos
Autores principales: Castro-Dopico, Tomas, Fleming, Aaron, Dennison, Thomas W., Ferdinand, John R., Harcourt, Katherine, Stewart, Benjamin J., Cader, Zaeem, Tuong, Zewen K., Jing, Chenzhi, Lok, Laurence S.C., Mathews, Rebeccah J., Portet, Anaïs, Kaser, Arthur, Clare, Simon, Clatworthy, Menna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351110/
https://www.ncbi.nlm.nih.gov/pubmed/32640223
http://dx.doi.org/10.1016/j.celrep.2020.107857