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WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair

The Fanconi anemia (FA) pathway repairs DNA interstrand crosslinks (ICLs). Many FA proteins are recruited to ICLs in a timely fashion so that coordinated repair can occur. However, the mechanism of this process is poorly understood. Here, we report the purification of a FANCD2-containing protein com...

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Detalles Bibliográficos
Autores principales: Socha, Anna, Yang, Di, Bulsiewicz, Alicja, Yaprianto, Kelvin, Kupculak, Marian, Liang, Chih-Chao, Hadjicharalambous, Andreas, Wu, Ronghu, Gygi, Steven P., Cohn, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351111/
https://www.ncbi.nlm.nih.gov/pubmed/32640220
http://dx.doi.org/10.1016/j.celrep.2020.107850