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A Non-Replicative Role of the 3′ Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation

Dengue virus (DENV) and Zika virus (ZIKV), members of the Flavivirus genus, rearrange endoplasmic reticulum membranes to induce invaginations known as vesicle packets (VPs), which are the assumed sites for viral RNA replication. Mechanistic information on VP biogenesis has so far been difficult to a...

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Detalles Bibliográficos
Autores principales: Cerikan, Berati, Goellner, Sarah, Neufeldt, Christopher John, Haselmann, Uta, Mulder, Klaas, Chatel-Chaix, Laurent, Cortese, Mirko, Bartenschlager, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351112/
https://www.ncbi.nlm.nih.gov/pubmed/32640225
http://dx.doi.org/10.1016/j.celrep.2020.107859