Asymmetric Diels–Alder reaction of 3-(acyloxy)acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors

We describe here our investigation of the asymmetric Diels–Alder reaction of chiral 3-(acyloxy)acryloyl oxazolidinones as dienophiles in various Lewis-acid promoted reactions with cyclopentadiene. The resulting highly functionalized cycloadducts are useful intermediates for the synthesis, particular...

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Detalles Bibliográficos
Autores principales: Ghosh, Arun K., Grillo, Alessandro, Kovela, Satish, Brindisi, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351138/
https://www.ncbi.nlm.nih.gov/pubmed/32655859
http://dx.doi.org/10.1039/c9ra10178k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351138/
https://www.ncbi.nlm.nih.gov/pubmed/32655859
http://dx.doi.org/10.1039/c9ra10178k

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