Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia

OBJECTIVE(S): The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: The study included 74 ALL patients. Polymerase...

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Detalles Bibliográficos
Autores principales: Esmaili, Mohammad Ali, Kazemi, Ahmad, Faranoush, Mohammad, Mellstedt, Hakan, Zaker, Farhad, Safa, Majid, Mehrvar, Narjes, Rezvany, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351433/
https://www.ncbi.nlm.nih.gov/pubmed/32695297
http://dx.doi.org/10.22038/ijbms.2020.41754.9858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351433/
https://www.ncbi.nlm.nih.gov/pubmed/32695297
http://dx.doi.org/10.22038/ijbms.2020.41754.9858

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