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Soluble uric acid induces inflammation via TLR4/NLRP3 pathway in intestinal epithelial cells

OBJECTIVE(S): Hyperuricemia is a risk for cardiovascular and metabolic diseases, but the mechanism is ambiguous. Increased intestinal permeability is correlated with metabolic syndrome risk factors. Intestinal epithelial cells play a pivotal role in maintaining intestinal permeability. Uric acid is...

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Detalles Bibliográficos
Autores principales: Ma, Chunling, Yang, Xiaomin, Lv, Qiulan, Yan, Zhimei, Chen, Zeqing, Xu, Daxing, Liu, Xiu, Yang, Wan, Xing, Shichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351448/
https://www.ncbi.nlm.nih.gov/pubmed/32695290
http://dx.doi.org/10.22038/ijbms.2020.44948.10482