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Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response

Fibrotic disorders represent common complex disease pathologies that are therapeutically challenging. Inflammation is associated with numerous fibrotic pathogeneses; however, its role in the multifaceted mechanisms of fibrosis remains unclear. IL-13 is implicated in aberrant responses involved in fi...

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Detalles Bibliográficos
Autores principales: Akbar, Moeed, Garcia-Melchor, Emma, Chilaka, Sabarinadh, Little, Kevin J., Sood, Shatakshi, Reilly, James H., Liew, Foo Y., McInnes, Iain B., Millar, Neal L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351483/
https://www.ncbi.nlm.nih.gov/pubmed/32695877
http://dx.doi.org/10.1126/sciadv.aaz8272