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Robust light–dark patterns and reduced amyloid load in an Alzheimer’s disease transgenic mouse model
Circadian disruption resulting from exposure to irregular light–dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer’s disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. bright-ligh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351709/ https://www.ncbi.nlm.nih.gov/pubmed/32651420 http://dx.doi.org/10.1038/s41598-020-68199-5 |