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Generation of a canine anti-canine CD20 antibody for canine lymphoma treatment

Lymphoma is the most common hematological cancer in dogs. Canine diffuse large B cell lymphoma shows a relatively good response to treatment with multi-agent cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy; however, the 2-year survival rate is as low as 20%. For human...

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Detalles Bibliográficos
Autores principales: Mizuno, Takuya, Kato, Yukinari, Kaneko, Mika K., Sakai, Yusuke, Shiga, Toshinori, Kato, Masahiro, Tsukui, Toshihiro, Takemoto, Hirofumi, Tokimasa, Akio, Baba, Kenji, Nemoto, Yuki, Sakai, Osamu, Igase, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351721/
https://www.ncbi.nlm.nih.gov/pubmed/32651429
http://dx.doi.org/10.1038/s41598-020-68470-9