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Tract-specific analysis improves sensitivity of spinal cord diffusion MRI to cross-sectional and longitudinal changes in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease that causes progressive degeneration of motor neurons in the brain and the spinal cord. Corticospinal tract degeneration is a defining feature of ALS. However, there have been very few longitudinal, controlled studie...

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Detalles Bibliográficos
Autores principales: Pisharady, Pramod Kumar, Eberly, Lynn E., Cheong, Ian, Manousakis, Georgios, Guliani, Gaurav, Clark, H. Brent, Bathe, Mark, Walk, David, Lenglet, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351722/
https://www.ncbi.nlm.nih.gov/pubmed/32651439
http://dx.doi.org/10.1038/s42003-020-1093-z