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Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects
The enzyme nicotidamide-N-methyltransferase (NNMT) regulates adipose tissue energy expenditure through increasing nicotinamide adenosine dinucleotide (NAD(+)) content. NNMT methylates nicotinamide to N(1)-methylnicotidamide (MNA-1) using S-adenosyl methionine. The rs694539 NNMT polymorphism is assoc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351746/ https://www.ncbi.nlm.nih.gov/pubmed/32651404 http://dx.doi.org/10.1038/s41598-020-67832-7 |