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Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown. Here we study the nanoscale organization of pathological ECS in adult...

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Detalles Bibliográficos
Autores principales: Soria, Federico N., Paviolo, Chiara, Doudnikoff, Evelyne, Arotcarena, Marie-Laure, Lee, Antony, Danné, Noémie, Mandal, Amit Kumar, Gosset, Philippe, Dehay, Benjamin, Groc, Laurent, Cognet, Laurent, Bezard, Erwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351768/
https://www.ncbi.nlm.nih.gov/pubmed/32651387
http://dx.doi.org/10.1038/s41467-020-17328-9