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Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types

PURPOSE: Early in mammalian eye development, VSX2, BRN3b, and RCVRN expression marks neural retinal progenitors (NRPs), retinal ganglion cells (RGCs), and photoreceptors (PRs), respectively. The ability to create retinal organoids from human induced pluripotent stem cells (hiPSC) holds great potenti...

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Detalles Bibliográficos
Autores principales: Lam, Phuong T., Gutierrez, Christian, Del Rio-Tsonis, Katia, Robinson, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352077/
https://www.ncbi.nlm.nih.gov/pubmed/32714647
http://dx.doi.org/10.1167/tvst.9.3.21