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Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types
PURPOSE: Early in mammalian eye development, VSX2, BRN3b, and RCVRN expression marks neural retinal progenitors (NRPs), retinal ganglion cells (RGCs), and photoreceptors (PRs), respectively. The ability to create retinal organoids from human induced pluripotent stem cells (hiPSC) holds great potenti...
Autores principales: | Lam, Phuong T., Gutierrez, Christian, Del Rio-Tsonis, Katia, Robinson, Michael L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352077/ https://www.ncbi.nlm.nih.gov/pubmed/32714647 http://dx.doi.org/10.1167/tvst.9.3.21 |
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