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Non-invasive characterization of amyotrophic lateral sclerosis in a hTDP-43(A315T) mouse model: A PET-MR study
Currently TAR DNA binding protein 43 (TDP-43) pathology, underlying Amyotrophic Lateral Sclerosis (ALS), remains poorly understood which hinders both clinical diagnosis and drug discovery efforts. To better comprehend the disease pathophysiology, positron emission tomography (PET) and multi-parametr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352080/ https://www.ncbi.nlm.nih.gov/pubmed/32653817 http://dx.doi.org/10.1016/j.nicl.2020.102327 |