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The m(6)A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells

The dynamic N(6)-methyladenosine (m(6)A) modification of mRNA plays a role in regulating gene expression and determining cell fate. However, the functions of m(6)A mRNA modification in bladder cancer stem cells (BCSCs) have not been described. Here, we show that global RNA m(6)A abundance and the ex...

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Detalles Bibliográficos
Autores principales: Gao, Qian, Zheng, Jin, Ni, Zegui, Sun, Pengli, Yang, Congcong, Cheng, Maosheng, Wu, Mingqing, Zhang, Xiuhong, Yuan, Lin, Zhang, Yingyin, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352121/
https://www.ncbi.nlm.nih.gov/pubmed/32676121
http://dx.doi.org/10.1155/2020/8849218