Cargando…
The m(6)A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells
The dynamic N(6)-methyladenosine (m(6)A) modification of mRNA plays a role in regulating gene expression and determining cell fate. However, the functions of m(6)A mRNA modification in bladder cancer stem cells (BCSCs) have not been described. Here, we show that global RNA m(6)A abundance and the ex...
Autores principales: | Gao, Qian, Zheng, Jin, Ni, Zegui, Sun, Pengli, Yang, Congcong, Cheng, Maosheng, Wu, Mingqing, Zhang, Xiuhong, Yuan, Lin, Zhang, Yingyin, Li, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352121/ https://www.ncbi.nlm.nih.gov/pubmed/32676121 http://dx.doi.org/10.1155/2020/8849218 |
Ejemplares similares
-
SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer
por: Zhu, Fengyu, et al.
Publicado: (2017) -
AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs
por: Zhou, Chen-chen, et al.
Publicado: (2017) -
AFF3 upregulation mediates tamoxifen resistance in breast cancers
por: Shi, Yawei, et al.
Publicado: (2018) -
m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
por: Cui, Qi, et al.
Publicado: (2017) -
AFF3-DNA methylation interplay in maintaining the mono-allelic expression pattern of XIST in terminally differentiated cells
por: Zhang, Yue, et al.
Publicado: (2018)