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Cisplatin Resistance in Testicular Germ Cell Tumors: Current Challenges from Various Perspectives

Testicular germ cell tumors share a marked sensitivity to cisplatin, contributing to their overall good prognosis. However, a subset of patients develop resistance to platinum-based treatments, by still-elusive mechanisms, experiencing poor quality of life due to multiple (often ineffective) interve...

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Detalles Bibliográficos
Autores principales: Lobo, João, Jerónimo, Carmen, Henrique, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352163/
https://www.ncbi.nlm.nih.gov/pubmed/32560427
http://dx.doi.org/10.3390/cancers12061601