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Good Cop, Bad Cop: Defining the Roles of Δ40p53 in Cancer and Aging

The tumour suppressor p53 is essential for maintaining DNA integrity, and plays a major role in cellular senescence and aging. Understanding the mechanisms that contribute to p53 dysfunction can uncover novel possibilities for improving cancer therapies and diagnosis, as well as cognitive decline as...

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Detalles Bibliográficos
Autores principales: Steffens Reinhardt, Luiza, Zhang, Xiajie, Wawruszak, Anna, Groen, Kira, De Iuliis, Geoffry N., Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352174/
https://www.ncbi.nlm.nih.gov/pubmed/32585821
http://dx.doi.org/10.3390/cancers12061659