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Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti-Cancer Quinone

Isoplumbagin (5-hydroxy-3-methyl-1,4-naphthoquinone), a naturally occurring quinone from Lawsonia inermis and Plumbago europaea, has been reported to have anti-inflammatory and antimicrobial activity. Inflammation has long been implicated in cancer progression. In this study, we examined the antican...

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Detalles Bibliográficos
Autores principales: Tsao, Yen-Chi, Chang, Yu-Jung, Wang, Chun-Hsien, Chen, Linyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352187/
https://www.ncbi.nlm.nih.gov/pubmed/32575541
http://dx.doi.org/10.3390/ijms21124378