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ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes

The accumulation of amyloid-β (Aβ) in the walls of capillaries and arteries as cerebral amyloid angiopathy (CAA) is part of the small vessel disease spectrum, related to a failure of elimination of Aβ from the brain. Aβ is eliminated along basement membranes in walls of cerebral capillaries and arte...

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Detalles Bibliográficos
Autores principales: Keable, Abby, O’Neill, Ronan, MacGregor Sharp, Matthew, Gatherer, Maureen, Yuen, Ho Ming, Johnston, David Annandale, Weller, Roy Oliver, Carare, Roxana Octavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352194/
https://www.ncbi.nlm.nih.gov/pubmed/32575521
http://dx.doi.org/10.3390/ijms21124371