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ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes
The accumulation of amyloid-β (Aβ) in the walls of capillaries and arteries as cerebral amyloid angiopathy (CAA) is part of the small vessel disease spectrum, related to a failure of elimination of Aβ from the brain. Aβ is eliminated along basement membranes in walls of cerebral capillaries and arte...
Autores principales: | Keable, Abby, O’Neill, Ronan, MacGregor Sharp, Matthew, Gatherer, Maureen, Yuen, Ho Ming, Johnston, David Annandale, Weller, Roy Oliver, Carare, Roxana Octavia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352194/ https://www.ncbi.nlm.nih.gov/pubmed/32575521 http://dx.doi.org/10.3390/ijms21124371 |
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