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Bad Neighborhood: Fibrotic Stroma as a New Player in Melanoma Resistance to Targeted Therapies

Current treatments for metastatic cutaneous melanoma include immunotherapies and drugs targeting key molecules of the mitogen-activated protein kinase (MAPK) pathway, which is often activated by BRAF driver mutations. Overall responses from patients with metastatic BRAF mutant melanoma are better wi...

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Detalles Bibliográficos
Autores principales: Diazzi, Serena, Tartare-Deckert, Sophie, Deckert, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352197/
https://www.ncbi.nlm.nih.gov/pubmed/32466585
http://dx.doi.org/10.3390/cancers12061364