Revisiting NO(2) as Protecting Group of Arginine in Solid-Phase Peptide Synthesis

The protection of side-chain arginine in solid-phase peptide synthesis requires attention since current protecting groups have several drawbacks. Herein, the NO(2) group, which is scarcely used, has been revisited. This work shows that it prevents the formation of δ-lactam, the most severe side-reac...

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Detalles Bibliográficos
Autores principales: Alhassan, Mahama, Kumar, Ashish, Lopez, John, Albericio, Fernando, de la Torre, Beatriz G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352207/
https://www.ncbi.nlm.nih.gov/pubmed/32586051
http://dx.doi.org/10.3390/ijms21124464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352207/
https://www.ncbi.nlm.nih.gov/pubmed/32586051
http://dx.doi.org/10.3390/ijms21124464

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